𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1α,25-dihydroxyvitamin D3 and 20-epi-2-methyl-1α,25-dihydroxyvitamin D3

✍ Scribed by Hiroaki Takayama; Katsuhiro Konno; Toshie Fujishima; Shojiro Maki; Zhaopeng Liu; Daishiro Miura; Manabu Chokki; Seiichi Ishizuka; Connie Smith; Hector F. DeLuca; Kimie Nakagawa; Mayuko Kurobe; Toshio Okano


Book ID
117213275
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
623 KB
Volume
66
Category
Article
ISSN
0039-128X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Concise synthesis and biological activit
✍ Shinobu Honzawa; Yoshitomo Suhara; Ken-ichi Nihei; Nozomi Saito; Seishi Kishimot 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 216 KB

We found a concise route to the Trost A-ring precursor enyne for synthesizing 2a-alkylated 1a,25-dihydroxyvitamin D 3 (1) from d-glucose. The enynes were coupled with the 20-epi-CD ring part to study the effect of the double modification of 2asubstitution and 20-epimerization upon biological activit