## BACKGROUND. Numerous clinical reports have raised the possibility that laparoscopic cancer surgery has an inherently detrimental effect on tumor growth. The aim of the current study was to examine the influence of a pneumoperitoneum on the morphology of the peritoneum and the intraperitoneal tu
Systematic review of the safety and effectiveness of methods used to establish pneumoperitoneum in laparoscopic surgery
β Scribed by T. L. Merlin; J. E. Hiller; G. J. Maddern; G. G. Jamieson; A. R. Brown; A. Kolbe
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 159 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-1323
- DOI
- 10.1002/bjs.4203
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Background
A systematic review was conducted to determine which of the methods of obtaining peritoneal access and establishing pneumoperitoneum is the safest and most effective.
Methods
Studies that met the inclusion criteria were identified from six bibliographic databases up to May 2002, the internet, hand-searches and reference lists. They were critically appraised using a validated checklist and data were extracted using standardized protocols.
Results
Meta-analysis of prospective, non-randomized studies of open versus closed (needle/trocar) access indicated a trend during open access towards a reduced risk of major complications (pooled relative risk (RRp) 0Β·30, 95 per cent confidence interval (c.i.) 0Β·09 to 1Β·03). Open access was also associated with a trend towards a reduced risk of access-site herniation (RRp 0Β·21, 95 per cent c.i. 0Β·04 to 1Β·03) and, in non-obese patients, a 57 per cent reduced risk of minor complications (RRp 0Β·43, 95 per cent c.i. 0Β·20 to 0Β·92) and a trend for fewer conversions to laparotomy (RRp 0Β·21, 95 per cent c.i. 0Β·04 to 1Β·17). Data on major complications in studies of direct trocar versus needle/trocar access were inconclusive. Minor complications in randomized controlled trials were fewer with direct trocar access (RRp 0Β·19, 95 per cent c.i. 0Β·09 to 0Β·40), predominantly owing to a reduction in extraperitoneal insufflation.
Conclusion
The evidence on the comparative safety and effectiveness of the different access methods was not definitive, but there were trends in the data that merit further exploration.
π SIMILAR VOLUMES
## SUMMARY This paper presents the findings of a systematic review of full or partial economic evaluations that included questions to service users or their carers to elicit information on the types, amounts or costs of communityβbased formal social care support provided to people 65βyears and olde
## Abstract ## Objectives To explore the feasibility and effectiveness of brief interventions to prevent depression in older subjects. ## Method MEDLINE, PsycINFO and HealthStar were searched for potentially relevant articles published from January 1966 to June 2003, January 1974 to June 2003 an
recent Darzi report 1 to see that patientrelated outcomes, and quality of life in particular, are likely to become more dominant within our clinical practice. We believe that as our understanding of this type of data increases, so too will their clinical applications. Mr Lee is right to raise conce