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Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

✍ Scribed by Piton, A; Gauthier, J; Hamdan, F F; Lafrenière, R G; Yang, Y; Henrion, E; Laurent, S; Noreau, A; Thibodeau, P; Karemera, L; Spiegelman, D; Kuku, F; Duguay, J; Destroismaisons, L; Jolivet, P; Côté, M; Lachapelle, K; Diallo, O; Raymond, A; Marineau, C; Champagne, N; Xiong, L; Gaspar, C; Rivière, J-B; Tarabeux, J; Cossette, P; Krebs, M-O; Rapoport, J L; Addington, A; DeLisi, L E; Mottron, L; Joober, R; Fombonne, E; Drapeau, P; Rouleau, G A

Book ID
119739132
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
659 KB
Volume
16
Category
Article
ISSN
1359-4184

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## Abstract Autism spectrum disorders (ASD) are complex genetic disorders more frequently observed in males. Skewed X chromosome inactivation (XCI) is observed in heterozygous females carrying gene mutations involved in several X‐linked syndromes. In this study, we aimed to estimate the role of X‐l