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Systematic interpretation of genetic interactions using protein networks

✍ Scribed by Kelley, Ryan; Ideker, Trey


Book ID
109908563
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
598 KB
Volume
23
Category
Article
ISSN
1087-0156

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## Abstract It is believed that interactions among genes (epistasis) may play an important role in susceptibility to common diseases (Moore and Williams [2002]. Ann Med 34:88–95; Ritchie et al. [2001]. Am J Hum Genet 69:138–147). To study the underlying genetic variants of diseases, genome‐wide ass