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Systematic discovery of analogous enzymes in thiamin biosynthesis

✍ Scribed by Morett, Enrique; Korbel, Jan O; Rajan, Emmanuvel; Saab-Rincon, Gloria; Olvera, Leticia; Olvera, Maricela; Schmidt, Steffen; Snel, Berend; Bork, Peer

Book ID
109911101
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
735 KB
Volume
21
Category
Article
ISSN
1087-0156

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## Abstract Thiamin (vitamin B1) is an essential molecule for all living organisms. Its major biologically active derivative is thiamin diphosphate, which serves as a cofactor for several enzymes involved in carbohydrate and amino acid metabolism. Important new functions for thiamin and its phospha