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Synthèse D'α-(Arylamino)Benzylphosphonates De Bis-β'-Chloréthyle

✍ Scribed by Robert René Smolders; Dominique Brunin; Frédéric Sarto


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
182 KB
Volume
97
Category
Article
ISSN
0037-9646

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Reactions of bridged dicarboxylic anhydride derivatives with sodium aide in THF give the corresponding, N-tert-butyloxycarbonyl p-minoesters Z(a-c), which can be cyclized to oxanorborno-and norbornouracils &(a-c). Pyrolysis of these adducts leads to dehydro-p-alanine 5 and oxauracil 1.