𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-κB and Notch1 signaling

✍ Scribed by Xiaohua Gao; Dorrah Deeb; Hao Jiang; Yongbo Liu; Scott A. Dulchavsky; Subhash C. Gautam

Publisher
Springer US
Year
2007
Tongue
English
Weight
483 KB
Volume
84
Category
Article
ISSN
0167-594X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Down-regulation of Notch-1 and Jagged-1
Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways
✍ Zhiwei Wang; Yiwei Li; Sanjeev Banerjee; Dejuan Kong; Aamir Ahmad; Veronique Nog 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 412 KB 👁 1 views

## Abstract Notch signaling is involved in a variety of cellular processes, such as cell fate specification, differentiation, proliferation, and survival. Notch‐1 over‐expression has been reported in prostate cancer metastases. Likewise, Notch ligand Jagged‐1 was found to be over‐expressed in metas

Differential regulation of cyclooxygenas
Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-κB signaling cascade
✍ France Vaillancourt; Barbara Morquette; Qin Shi; Hassan Fahmi; Patrick Lavigne; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 411 KB 👁 1 views

## Abstract 4‐hydroxynonenal (HNE), a lipid peroxidation end product, is produced abundantly in osteoarthritic (OA) articular tissues and was recently identified as a potent catabolic factor in OA cartilage. In this study, we provide additional evidence that HNE acts as an inflammatory mediator by