Disruption of the interaction of T cells
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Maximilian Zeyda; Marko Poglitsch; René Geyeregger; Josef S. Smolen; Gerhard J.
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Article
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2005
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John Wiley and Sons
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English
⚖ 353 KB
👁 1 views
## Abstract ## Objective Leflunomide, a potent disease‐modifying antirheumatic drug of the isoxazole class, exhibits antiinflammatory, antiproliferative, and immunosuppressive effects by largely unknown mechanisms, although alterations of pyrimidine synthesis have been proposed. Successful immune