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Synthetic study on 1,3-polyols. Total synthesis of (4S, 6S, 8S, 10S, 12R, 14R, 16R, 18R, 20R) nonamethoxy-1-pentacosene from blue-green algae

✍ Scribed by Yuji Mori; Yasunori Kohchi; Toshimi Ota; Makoto Suzuki


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
135 KB
Volume
31
Category
Article
ISSN
0040-4039

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Hydrogenation of the ketone group in di-0-benzylderivative (8) of the known macrocyclic lactone zeralenone (7) using a novel chiral borane complex 3.BH3, prepared in situ, proceeded at lower temperatures with moderate diastereoselectivity ( -40%, d.e. at -60"). Unsaturated diastereomers 9 and 10 wer