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Synthetic studies towards paraherquamide F: synthesis of the 1,7-dihydropyrano[2,3-g]indole ring system

✍ Scribed by Rhona J. Cox; Robert M. Williams

Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 110 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)00220-4

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✦ Synopsis

A substituted 1,7-dihydropyrano[2,3-g]indole suitable for elaboration to paraherquamide F has been prepared in eight steps and 6% overall yield. The key steps are a Fischer indolization and a Claisen rearrangement.

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