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Synthetic Studies Toward Pectenotoxin 2. Part I. Stereocontrolled Access to the C 10 −C 22 Fragment

✍ Scribed by Aho, Jatta E.; Salomäki, Elina; Rissanen, Kari; Pihko, Petri M.


Book ID
126102498
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
259 KB
Volume
10
Category
Article
ISSN
1523-7060

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Synthetic studies directed toward amphid
✍ Praveen Kommana; Seung Won Chung; William A. Donaldson 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 205 KB

Model compounds (11 and 12) for the C1-C10 tetrahydropyran fragment of amphidinol 2 were prepared from (2S)-benzyloxypropanal in 9 steps. The synthetic route relied on diastereoselective diene-aldehyde cycloaddition, stereoselective C-allylation, and reagent based enantioselective aldehyde allylatio