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Synthetic studies toward marine toxic polyethers (1) a stereocontrolled synthesis of the C-segnent of okadaic acid

โœ Scribed by Minoru Isobe; Yoshiyasu Ichikawa; Hisanori Masaki; Toshio Goto


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
237 KB
Volume
25
Category
Article
ISSN
0040-4039

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Synthetic studies toward marine toxic po
โœ Yoshiyasu Ichikawa; Minoru Isobe; Toshio Goto ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 259 KB

Part of okadaic acid la vas synthesized stereoselectively in the fora of 4a (involving C-16 through C-38 uith 10 asymaetric carbons), by coupling the equivalents of 2 and 3 as the synthetic segments Il and C (Scheme 1). the forser being prepared via 12 and 6 froa a D-glucopyranose derivative (Scheae