✦ LIBER ✦

Synthetic studies on apoptolidin: synthesis of the C1–C21 macrolide fragment

✍ Scribed by Kazunobu Toshima; Tsuyoshi Arita; Koji Kato; Daisuke Tanaka; Shuichi Matsumura

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 71 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01948-7

No coin nor oath required. For personal study only.

✦ Synopsis

The stereoselective and convergent synthesis of the C1-C21 macrocyclic segment (2) of the apoptosis inducing macrolide antibiotic, apoptolidin (1), is described.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthetic Studies o

ChemInform Abstract: Synthetic Studies on Apoptolidin: Synthesis of the C1—C21 Macrolide Fragment.

✍ Kazunobu Toshima; Tsuyoshi Arita; Koji Kato; Daisuke Tanaka; Shuichi Matsumura 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 2 views

ChemInform Abstract: Studies on the Synt

ChemInform Abstract: Studies on the Synthesis of Apoptolidin A (I). Part 1. Synthesis of the C(1)—C(11) Fragment.

✍ Masaki Handa; Karl A. Scheidt; Martin Bossart; Nan Zheng; William R. Roush 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 22 KB 👁 2 views

ChemInform Abstract: Synthetic Studies o

ChemInform Abstract: Synthetic Studies on Tedanolide: Stereoselective Synthesis of the C13—C21 Fragment.

✍ Su Ho Park; Jae Ki Min; Se Hwan Park; Hyo Won Lee 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Synthetic studies toward potent cytostat

Synthetic studies toward potent cytostatic macrolide rhizopodin: stereoselective synthesis of the C16–C28 fragment

✍ Tushar Kanti Chakraborty; Midde Sreekanth; Kiran Kumar Pulukuri 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 325 KB

ChemInform Abstract: Synthetic Study on

ChemInform Abstract: Synthetic Study on a 26-Membered Macrolide, Amphidinolide B: Synthesis of the C1—C13 Fragment.

✍ K. OHI; K. SHIMA; K. HAMADA; Y. SAITO; N. YAMADA; S. OHBA; S. NISHIYAMA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 2 views

Synthetic studies on spongistatins: synt

Synthetic studies on spongistatins: synthesis of the C29–C44 fragment

✍ Mohammad Samadi; Christian Munoz-Letelier; Stéphane Poigny; Michèle Guyot 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 173 KB

A convergent synthesis of the C29-C44 fragment, the common subunit of the spongipyran macrolides is described. The key step of the synthesis is the C-glycosidation reaction which is based on coupling of the lithiated F-ring sulfone with the E-ring aldehyde, and subsequent reductive desulfonylation t