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Synthetic studies on altohyrtins (spongistatins): synthesis of the C15–C28 (CD) spiroacetal portion

✍ Scribed by Takeshi Terauchi; Taro Terauchi; Ippei Sato; Tomoharu Tsukada; Naoki Kanoh; Masaya Nakata

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
266 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

The C15-C28 portion of altohyrtins (spongistatins) was prepared in a convergent manner from methyl (S)-3hydroxy-2-methylpropionate, D-arabitol, and diacetone-D-glucose via dithiane couplings with epoxides as the key segment coupling process.

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