Synthetic studies of viridenomycin. Construction of the cyclopentene carboxylic acid part

✍ Scribed by Jun Ishihara; Koji Hagihara; Hiroyuki Chiba; Kouichi Ito; Yumiko Yanagisawa; Kiichiro Totani; Kin-ichi Tadano

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 157 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00013-7

✦ Synopsis

A highly functionalized cyclopentene carboxylic acid derivative, as an advanced synthetic intermediate of viridenomycin, was synthesized. The synthesis commenced with the previously reported highly functionalized tetrahydrofuran derivative prepared from D-glucose. The stereochemical confirmation of the present final compound was conducted by comparison with a compound synthesized very recently by the Meyers group.