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Synthetic studies of potential antimetabolites. XIII. Synthesis of 7-amino-3-β-d-ribofuranosyl-3H-imidazo[4,5-b] pyridine (1-deazaadenosine) and related nucleosides

✍ Scribed by Tokuo Itoh; Shigeru Kitano; Yoshihisa Mizuno


Book ID
112122661
Publisher
Journal of Heterocyclic Chemistry
Year
1972
Tongue
English
Weight
499 KB
Volume
9
Category
Article
ISSN
0022-152X

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2-Amino-8-(2-deoxy-2-fluoro-β-D-arabinof
✍ Virginie Glaçon; Frank Seela 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 German ⚖ 112 KB

## Abstract Nucleobase‐anion glycosylation of 2‐[(2‐methyl‐1‐oxopropyl)amino]imidazo[1,2‐__a__]‐1,3,5‐triazin‐4(8__H__)‐one (**6**) with 3,5‐di‐__O__‐benzoyl‐2‐deoxy‐2‐fluoro‐__α__‐D‐arabinofuranosyl bromide (**8**) furnishes a mixture of the benzoyl‐protected anomeric 2‐amino‐8‐(2‐deoxy‐2‐fluoro‐D