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Synthetic Scheme for the Preparation of 13C-Labeled 2,7-Dimethylocta2,4,6-triene-1,8-dial, the Central Part of Carotenoids

✍ Scribed by Arjan A. C. van Wijk; Johan Lugtenburg


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
91 KB
Volume
2002
Category
Article
ISSN
1434-193X

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✦ Synopsis


Starting from acetic acid and methyl iodide an efficient modular synthetic scheme has been developed for the synthesis of 13 C-labeled 2,7-dimethylocta-2,4,6-triene-1,8-dial, which is a suitable building block in the synthesis of carotenoids with tenfold 13 C-enrichment in the central part.


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Synthesis of 13C-labelled (all-E,3R,3′R)
✍ Frederick Khachik; Gary R. Beecher; Betty W. Li; Gerhard Englert 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 668 KB

## Abstract The title compound (10) has been synthesized from all‐E‐2,7‐ dimethylocta‐2,4,6‐triene‐1,8‐dial (C~10~‐dialdehyde, 8) labelled with four ^13^C from commercially available and relatively inexpensive starting materials. The key starting material in this synthesis, (EtO)~2~P(O)^13^CHMe^13^