Synthetic Peptides in HIV Antibody Screening and Typing
✍ Scribed by OLIVIERO E. VARNIER; ALE NÄRVÄNEN; MIRJA KORKOLAINEN; FLAVIA LILLO; SARI KONTIO; JOSEPH ELM; JUKKA SUNI; ANTTI VAHERI; MARJA-LIISA HUHTALA
- Book ID
- 119866533
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 569 KB
- Volume
- 626
- Category
- Article
- ISSN
- 0890-6564
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Five peptides derived from human immuno deficiency virus (HIV-1) gp41 transmembrane protein have been synthesized: M9 (610-618), M12 (598609), M15 (600614), M21(584-604) and M23 (587409). These sequences partially overlap in the region vicinal to the immunodominant epitope CSGKLIC, between two cyste
## Abstract We have analyzed the suitability of six antigenic peptides from several HIV‐1 structural proteins (namely gp41, gp120, p17, and p24), as anti‐HIV‐1 antibody receptors in an allosteric enzymatic biosensor. These peptides were inserted in a solvent‐exposed surface of __Escherichia coli__