Synthetic Microbiol Chemistry, XXIX!. Synthesis of Both the Enantiomers of Incrustoporin, an Antibiotic from Incrustoporia carneola

✍ Scribed by Yajima, Arata ;Mori, Kenji

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 298 KB
• Volume: 1996
• Category: Article
• ISSN: 0947-3440
• DOI: 10.1002/jlac.199619960707

✦ Synopsis

Abstract

Both the enantiomers of incrustoporin (2‐p‐tolyl‐2‐hexen‐4‐olide, 1) were synthesized by starting from methyl p‐tolylacetate (2) and (S)‐1,2‐epoxybutane (3). The naturally occurring compound 1 was shown to possess the R configuration.