Synthetic methods in drug discovery. Volume 2

✍ Scribed by Blakemore, David; Doyle, Paul; Fobian, Yvette

Publisher: Royal Society of Chemistry
Year: 2016
Tongue: English
Leaves: 536
Series: RSC drug discovery series 53
Edition: Gld
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Building on key reactions presented in Volume 1, Synthetic Methods in Drug Discovery Volume 2 covers a range of important reaction types including organometallic chemistry, fluorination approaches and asymmetric methods as well as new and exciting areas such as Csp2-Csp3 couplings, catalytic amide bond forming reactions, hydrogen borrowing chemistry and methods to access novel motifs and monomers. This book provides both academic and industrial perspectives on key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Moreover, key opportunities in expanding chemical space are presented, including the increasingly important syntheses that introduce three-dimensional molecular shape. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry

✦ Subjects

Drug development.;MEDICAL / Pharmacology;Drug Discovery;methods.

📜 SIMILAR VOLUMES

Synthetic methods in drug discovery. Vol

📁 Synthetic methods in drug discovery. Volume 1

✍ Blakemore, David; Doyle, Paul; Fobian, Yvette 📂 Library 📅 2016 🏛 Royal Society of Chemistry 🌐 English

Synthetic Methods in Drug Discovery Volume 1 focusses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging area

Computational Drug Discovery, 2 Volumes:

📁 Computational Drug Discovery, 2 Volumes: Methods and Applications

✍ Poongavanam V., Ramaswamy V. (ed.) 📂 Library 📅 2024 🏛 WILEY-VCH 🌐 English

Computational Drug Discovery: Methods and Applications (2 volume set) covers a wide range of cutting-edge computational technologies and computational chemistry methods that are transforming drug discovery. The book delves into recent advances, particularly focusing on artificial intelligence (AI) a

Frontiers in CNS Drug Discovery Volume 2

📁 Frontiers in CNS Drug Discovery Volume 2

✍ Atta-ur-Rahman; M. Iqbal Choudhary 📂 Library 📅 2013 🏛 Bentham Science Publishers 🌐 English

"Frontiers in CNS Drug Discovery" is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistr

Frontiers in Drug Design and Discovery,

📁 Frontiers in Drug Design and Discovery, Volume (2)

✍ ur-Rahman, Atta- Caldwell, Gary W. Choudhary, M. Iqbal 📂 Library 📅 2006 🏛 Bentham Science Publishers 🌐 English

Successful Drug Discovery, Volume 2

📁 Successful Drug Discovery, Volume 2

✍ Janos Fischer 📂 Library 📅 2016 🏛 Wiley-VCH 🌐 English

Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it to market tell the story of the drug's discovery and development and relate the often twisted route from the first candidate molecule to the final ma

Epigenetic Targets in Drug Discovery (Me

📁 Epigenetic Targets in Drug Discovery (Methods and Principles in Medicinal Chemistry, Volume 42)

✍ Wolfgang Sippl, Manfred Jung, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers 📂 Library 📅 2009 🌐 English