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Synthetic Methods, Anticoagulation Activity and Toxicity of 2-Acyl Substituted Derivatives of Indane-1,3-dione

✍ Scribed by S. D. Karakotov; V. V. Shapilova; A. L. Chimishkyan; L. Ya. Kozenasheva

Publisher: John Wiley and Sons
Year: 2005
Weight: 8 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200518241

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## Abstract A novel synthesis of thiadiazoline derivatives **12** and **14** __via__ treatment of indane‐1,3‐dione‐2‐thiocarboxanilides (**5**) with hydrazonoyl halides **1** and **2** is reported. Also, active chloromethylene compounds **15** react with **5** to give thiazole derivatives **19**. ©