Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway
✍ Scribed by Yan Wang; Ingo H Engels; Deborah A Knee; Marc Nasoff; Quinn L Deveraux; Kim C Quon
- Book ID
- 114413433
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 600 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1535-6108
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Vitamin E derivative RRR‐α‐tocopherol ether‐linked acetic acid analog (α‐TEA) induces apoptosis in MCF‐7 and HCC‐1954 human breast cancer cells in a dose‐ and time‐dependent manner. α‐TEA induces increased levels of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) and dea
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of a diverse range of chemicals, including the environmental contaminant 2,3,7,8-tetrachlorodibenzop-dioxin (TCDD, dioxin). Although no endogenous physiologic