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Synthetic Lethal Relationships in the DNA Damage Response of Triple Negative Breast Cancer

✍ Scribed by M.P. Greenbaum; T.D. Wiltshire; G.G. Glick; J.A. Bauer; B.D. Lehmann; J.A. Pietenpol; D. Cortez

Book ID: 118455813
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 38 KB
Volume: 81
Category: Article
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2011.06.054

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## Abstract Triple‐negative breast cancer (TNBC) is defined by a lack of expression of estrogen, progesterone, and HER2 receptors, and genetically most of them fall into the basal subgroup of breast cancer. The important issue of TNBC is poorer clinical outcome and absence of effective targeted the