✦ LIBER ✦

Synthetic Extracellular Matrix Enhances Tumor Growth and Metastasis in an Orthotopic Mouse Model of Pancreatic Adenocarcinoma

✍ Scribed by Courtney L. Scaife; Jill E. Shea; Qiang Dai; Matthew A. Firpo; Glenn D. Prestwich; Sean J. Mulvihill

Publisher: Springer-Verlag
Year: 2007
Tongue: English
Weight: 256 KB
Volume: 12
Category: Article
ISSN: 1091-255X
DOI: 10.1007/s11605-007-0425-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthetic inhibitor of matrix metallopro

Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model

✍ Lein, Michael; Jung, Klaus; Le, Dinh K.; Hasan, Tayyaba; Ortel, Bernhard; Borche 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 1 views

BACKGROUND. Increased concentrations of metalloproteinases are associated with the invasive and metastatic behavior of several human malignant tumors. Normally, enzymatic activity is tightly regulated by nonspecific mechanisms and specific inhibitors. The aim of the study was to determine the potent

Regulated Expression of CCL21 in the Pro

Regulated Expression of CCL21 in the Prostate Tumor Microenvironment Inhibits Tumor Growth and Metastasis in an Orthotopic Model of Prostate Cancer

✍ Nazita Yousefieh; Suzanne M. Hahto; Amber L. Stephens; Richard P. Ciavarra 📂 Article 📅 2009 🏛 Springer Netherlands 🌐 English ⚖ 238 KB

CXCR4 peptide antagonist inhibits primar

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model

✍ Saima Hassan; Marguerite Buchanan; Kaushar Jahan; Adriana Aguilar-Mahecha; Louis 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 527 KB

## Abstract CXCR4 is a chemokine receptor implicated in the homing of cancer cells to target metastatic organs, which overexpress its ligand, stromal cell‐derived factor (SDF)‐1. To determine the efficacy of targeting CXCR4 on primary tumor growth and metastasis, we used a peptide inhibitor of CXCR