𝔖 Bobbio Scriptorium
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Synthetic entry into cyclopentyl analogs of muscarine

✍ Scribed by Richard S. Givens; Don R. Rademacher; Janet Kongs; John Dickerson


Book ID
104242986
Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
168 KB
Volume
15
Category
Article
ISSN
0040-4039

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✦ Synopsis


As a result of recent work, it is apparent that desether muscarine (a), the cyclopentyl analog of muscarine (Q, parallels the activity and specificity of muscarine at the cholinergic receptor. 2 This communication reports a stereoselective entry into the substituted cyclopentane system. Ho +.. Earlier we reported a photochemical route 2b CHsn CH+ depicted in Scheme 1 which gave the desired desether muscarine & in an overall yield of 4% from bromoformate z.3 Need for sufficient quantities of $ for resolution and oxidation 2b studies prompt-CH+-+ ed development of a second route.


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ChemInform Abstract: Synthesis and React
✍ T. TAKAYASU; K. ITO; M. NITTA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

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