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SYNTHETIC ENKEPHALINS Addicting Properties and Conformational Studies in Solution

โœ Scribed by FILIPPI, BRUNO ;GIUSTI, PIERO ;CIMA, LORENZO ;BORIN, GIANFRANCO ;RICCHELLI, FERNANDA ;MARCHIORI, FERNANDO

Book ID
115097530
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
464 KB
Volume
14
Category
Article
ISSN
0367-8377

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## Synopsis The synthesis of Leu-enkephalin selectively l70-enriched in Gly' and Gly3 is reported. The 170-nm chemical shifts of Leu5]-and [170-Gly3, Le~~l-enkephalins in H,O are almost identical and independent of the pH. Since hydrogen bonding is the dominant factor governing the chemical shifts