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Synthetic efforts directed towards the taxol skeleton. The saturated C-ring approach

โœ Scribed by K.J. Shea; C.D. Haffner


Book ID
108381632
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
278 KB
Volume
29
Category
Article
ISSN
0040-4039

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An elegant stereocontrolled synthesis of a highly functionalized C ring fragment of taxol ยฎ is d~-ribed. The route utilises a new Diels-Alder reaction followed by regioselective opening ofanhyth'ide, reductive dechlorination, Baeyer-Villiger oxidation of norbornenone system and stereodirected hydrob