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Synthetic butanolide and tetrahydrofuran lignans with platelet activating factor antagonist activity

โœ Scribed by SA Coran; M Bambagiotti-Alberti; F Melani; V Giannellini; FF Vincieri; N Mulinacci; R Sala; E Moriggi

Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
633 KB
Volume
26
Category
Article
ISSN
0223-5234

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Molecular modeling on platelet-activatin
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โœ Carlos M. R. De Sant'anna; Ricardo Bicca De Alencastro; Carlos A. M. Fraga; Elie ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 885 KB

Platelet-activating factor (PAF) is an autacoid derived from cellular membrane phospholipids in response to chemical or physical stimuli. It has been identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphocholine; the alkyl group is composed of 16 or 18 carbon atoms in human cells. PAF can cause a se