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Synthetic branched-chain analogs of distearoylphosphatidylcholine: structure-activity relationship in inhibiting and activating protein kinase C

✍ Scribed by Charp, Paul A.; Zhou, Qingzhong; Wood, Mervin G.; Raynor, Robert L.; Menger, Fredric M.; Kuo, J. F.


Book ID
127373653
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
753 KB
Volume
27
Category
Article
ISSN
0006-2960

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and His, was synthesized and the kinetics of their phosphorylation by protein kinase C was studied. All compounds, except the peptide with Pro at the position X, were effectively phosphorylated by this enzyme, and for these substrates the kinetic constants K m , maximal velocity constants V, and sec