Synthetic bioabsorbable microtubes for the treatment of surgical sites
β Scribed by Frank R. Cichocki Jr.; Gavin Chen; Jack Zhou; Meng Deng
- Book ID
- 103847266
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 847 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0928-4931
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β¦ Synopsis
Bioabsorbable polyglycolide-co-lactide microtubes have been developed for the continuous delivery of fluid medications directly to an operative site. Studies conducted with radio-opaque solution using porcine models indicated that infusion of fluids in the wound site was rapid and complete. The tissue reaction to the microtube was generally characterized as minimal to mild with complete absorption occurring within 56 days postimplantation. Processing-microstructure-property relationships and bio-degradation characteristics of the microtubes are presented.
π SIMILAR VOLUMES
This study was performed to investigate the potential utility of ofloxacin-impregnated bioabsorbable polymers for osteomyelitis therapy. Pseudomonas aeruginosa osteomyelitis was induced in 48 New Zealand White rabbits. Four weeks after infection, the animals were randomized to one of four treatment