Synthetic Approach to Tetrahydrofuran Units and Five-Membered Ring Lactones Fused to Hexopyranosides.
โ Scribed by Amelia P. Rauter; Olga Oliveira; Tana Canda; Estelle Leroi; Humberto Ferreira; Maria J. Ferreira; Jose A. Ascenso
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 329 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
## Abstract The utility of the previously reported MoritaโBaylisโHillman adducts (I) and the analogous Barbier adducts (V) for the synthesis of annulated derivatives of ฮฒโcarboline via ring closingโmetathesis is demonstrated.
endo-Fused lactone 3 was obtained in high yield from the mechanism of its formation and reactivity were investigated. Lactone 3 serves as key intermediate for lactol 1 which is a camphoracetic acid 2 with thionyl chloride and a subsequent reduction of intermediate 5 with tributyltin hydride. The use