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Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice

✍ Scribed by Shestakov, Andrey; Jenssen, Håvard; Hancock, Robert E.W.; Nordström, Inger; Eriksson, Kristina

Book ID
123386622
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
444 KB
Volume
100
Category
Article
ISSN
0166-3542

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## Abstract Experimental infection of the C3H/N mouse genital tract was demonstrated after intravaginal inoculation with herpes simplex virus type 2 (HSV‐2). About 75% of the infected animals died by Day 7, and 75% of the surviving animals had severe vaginitis or neurological signs on Day 7. Titers