## Abstract Preparation of 2,3‐Dimethyl‐5,6‐dihydro‐4__H__‐1,2‐oxaziniumiodide was achieved by N‐alkylation of 3‐methyl‐5,6‐dihydro‐4__H__‐1,2‐oxazine. Reactions with C‐nucleophiles led to the corresponding N‐methyl‐perhydro‐1,2‐oxazine derivatives. Reaction with sodium hydride in triglyme led to 3
Synthesis with 1,2-Oxazines. I. A Synthesis of 4,5-Dihydro-6H-1,2-Oxazin-6-one Derivatives
✍ Scribed by Bruno Hardegger; Shimon Shatzmiller
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- German
- Weight
- 271 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
A synthesis of some 4,5‐dihydro‐6__H__‐1,2‐oxazin‐6‐one derivatives is described.
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## Abstract Derivatives of the unknown 2‐amino‐6__H__‐1,3‐oxazin‐6‐one **2** have been synthesized for the first time in two steps and in excellent yields, starting from __N__‐cyanocarbonimidates **3a**–**c** and cyanoacetates. The structures of **2a**–**c** are assigned by NMR‐spectroscopic method