Synthesis, structure, and fungicidal activity of triorganotin (4H-1,2,4-triazol-4-yl)benzoates

✍ Scribed by Fang-Lin Li; Bin Dai; Hai-Bin Song; Na Mi; Liang-Fu Tang

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 182 KB
• Volume: 20
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20566

✦ Synopsis

A series of triorganotin (4H-1,2,4triazol-4-yl)benzoates have been synthesized by the reaction of 4-( 4H-1,2,4-triazol-4-yl)benzoic acid and 3-(4H-1,2,4-triazol-4-yl)benzoic acid with (R 3 Sn) 2 O (R = Et, n-Bu and Ph) or R 3 SnOH (R = p-tolyl and cyclohexyl). The molecular structure of tri( p-tolyl)tin 3-(4H-1,2,4-triazol-4-yl)benzoate determined by X-ray crystallography displays that the tin atom adopts a five-coordinate distorted trigonal bipyramidal geometry with the carboxyl oxygen atom and the nitrogen atom on 1-position of triazole ring occupying the apical position. Moreover, this complex forms a polymeric chain by the intermolecular Sn-N interactions. All these complexes show good antifungal activities in vitro against Alternaria solani, Cercospora arachidicola, Gibberella zeae, Physalospora piricola, and Botrytis cinerea.