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Synthesis, structure and cytotoxic activity of new 1-[5-organylsilyl(germyl)-2-furyl (thienyl)]nitroethenes

✍ Scribed by Luba Ignatovich; Velta Muravenko; Vitalijs Romanovs; Ilze Sleiksha; Irina Shestakova; Ilona Domrachova; Sergey Belyakov; Jury Popelis; Edmunds Lukevics

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 195 KB
Volume: 24
Category: Article
ISSN: 0268-2605
DOI: 10.1002/aoc.1712

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## Abstract As part of our ongoing research effort to develop new antimitotic agents based on the recently reported pyrimido[4,5‐__c__]quinoline‐1(2__H__)‐one ring skeleton, we were interested in identifying structural elements that contribute to the cytotoxicity of this class of compounds. The eff