Direct reaction of thiazolidine-2-thione (tzdtH), an anti-thyroidal agent with diiodine in a molar ratio of 1:2 caused the heterolytic cleavage of diiodine and formation of [{(tzdtH (1), whereas the reaction of benzothiazole-2-thione (bztzdtH) with diiodine in a molar ratio of 1:2 and 1:1 resulted
✦ LIBER ✦
Synthesis, Structural Characterization, and Computational Studies of Novel Diiodine Adducts with the Heterocyclic Thioamides N -Methylbenzothiazole-2-thione and Benzimidazole-2-thione: Implications with the Mechanism of Action of Antithyroid Drugs
✍ Scribed by Corban, Ghada J.; Hadjikakou, Sotiris K.; Hadjiliadis, Nick; Kubicki, Maciej; Tiekink, Edward R. T.; Butler, Ian S.; Drougas, Evangelos; Kosmas, Agnie M.
- Book ID
- 120387466
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 198 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0020-1669
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## Abstract The reaction of 2‐mercaptopyridine (C~5~H~5~NS or PYSH) with diiodine in a molar ratio of 1:2 in dichloromethane led to the oxidation and dimerization of the ligand and formation of [(PYS−PYSH)^+^·I~3~^−^]. The compound was characterised by elemental analysis, DTA‐TG, FT‐Raman, FT‐IR, U