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Synthesis, receptor binding, and target-tissue uptake of carbon-11 labeled carbamate derivatives of estradiol and hexestrol

โœ Scribed by Ouellet, Rene; Rousseau, Jacques; Brasseur, Nicole; Van Lier, Johan E.; Diksic, Mirko; Westera, Gerrit


Book ID
126460715
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
722 KB
Volume
27
Category
Article
ISSN
0022-2623

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Fluorine-18 labeled 11ฮฒ-substituted estr
โœ M. G. Pomper; A. Katzenellenbogen; R. D. Thomas; C. J. Mathias; H. van Brocklin; ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 152 KB

Estrogens labeled with fluorine-I 8 show selective receptor-mediated uptake into estrogen target tissues,' and one agent, 1 6u-[1~F]fluoroestradiol ( l ) , has been used to image estrogen receptor-positive human breast tumors.2 In order to improve on the uptake characteristics of 1, we have examined