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Synthesis, reactions and biological evaluation of some 1,2,4-triazine derivatives

✍ Scribed by A. K. Mansour; Mohga M. Eid; R. A. Hassan; A. Haemers; S. R. Pattyn; D. A. Vanden Berghe; L. Van Hoof

Book ID
112128835
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
266 KB
Volume
25
Category
Article
ISSN
0022-152X

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Synthesis, characterization and biologic
Synthesis, characterization and biological activity of some 1,2,4-triazine derivatives
✍ A. A. El-Barbary; M. A. Sakran; A. M. El-Madani; Claus Nielsen πŸ“‚ Article πŸ“… 2005 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 160 KB

## Abstract 4‐Amino‐6‐methyl‐3‐(2__H__)‐thioxo‐5‐(4__H__)‐oxo‐1,2,4‐triazine (**1**) was condensed with 2‐methyl (or phenyl)‐4__H__‐3,1‐benzoxazin‐4‐one (**5a,b**) in boiling acetic acid to give compounds **8‐11**. Reacting 1 with chloroacetyl chloride afforded the corresponding chloroacetamido and