Synthesis, properties and application of a novel series of one-ended monooleate-modified poly(ethylene glycol) with active carboxylic terminal

Synthesis of heterobifunctional poly(eth

Synthesis of heterobifunctional poly(ethylene glycol) with a primary amino group at one end and a carboxylate group at the other end

✍ Sheng Zhang; Jian Du; Rui Sun; Xiaopeng Li; Dejuan Yang; Shenglan Zhang; Chengdo 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 230 KB

A novel synthetic route to heterobifunctional poly(ethylene glycol) containing both amino and carboxylate terminal groups was established via anionic polymerization of ethylene oxide using (cyanomethyl)potassium as the initiator, followed by the successive conversion of the end-hydroxyl group to a p