AbstractÐFuro [3,4-d]pyrimidinones were found to be metabolites of dihydropyrimidinones such as 1a±b that are subtype-selective antagonists of the a 1a -adrenergic receptor. A versatile synthesis that provides access to furo [3,4-d]pyrimidinones in high yield and in enantiomerically pure forms is de
✦ LIBER ✦
Synthesis, Pharmacology and Pharmacokinetics of 3-(4-Arylpiperazin-1-ylalkyl)-uracils [cf. (V)] as Uroselective α1A-Antagonists.
✍ Scribed by F. J. Lopez; et al. et al.
- Book ID
- 101943788
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 79 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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