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Synthesis ofC1-symmetric primary-secondary diamines and their application in the enantioselective Henry reaction

✍ Scribed by Lili Zhang, Ming Liu, Shijun Ma…


Book ID
120948185
Publisher
SP Higher Education Press
Year
2013
Tongue
English
Weight
146 KB
Volume
7
Category
Article
ISSN
2095-0179

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Synthesis of Chiral 1,3-Diamines Derived
✍ Dr. Koichi Kodama; Kazuyuki Sugawara; Prof. Takuji Hirose 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

## Abstract In this study, 13 different chiral 1,3‐diamines were synthesized from (−)‐__cis__‐2‐benzamidocyclohexanecarboxylic acid. They were successfully applied as ligands in the Cu‐catalyzed asymmetric Henry reaction between benzaldehyde and nitromethane. It was confirmed that the enantioselect