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Synthesis of γ-keto carboxylic acids from γ-keto-α-chloro carboxylic acids via carbonylation—decarboxylation reactions catalysed by a palladium system

✍ Scribed by G. Cavinato; L. Toniolo


Publisher
Elsevier Science
Year
1993
Weight
598 KB
Volume
78
Category
Article
ISSN
0304-5102

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On the mechanism of the hydrogen transfe
✍ G. Cavinato; L. Toniolo 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 631 KB

The catalytic system PdCI,(PPh,),-HCI is highly active and selective in the hydrogen transfer reaction from H,O-CO to PhCOCH,CHOHCOOH which yields the corresponding y-keto acid PhCOCH,CH,COOH, with concomitant evolution of C02. An increase of temperature, pressure of carbon monoxide and catalyst con