The Rh-DuPHOS and Rh-BPE catalyzed hydrogenation of IS-substituted ¢x,[~,y,8-unsaturated amino acids establishes two contiguous stereogenic centers simultaneously. Both high regioselectivity and good to excellent enantioselectivity have been demonstrated in this process leading to I~-branched allyl
✦ LIBER ✦
Synthesis of β,γ-unsaturated amino acids as potential catalytic irreversible enzyme inhibitors
✍ Scribed by Brian W. Metcalf; Karin Jund
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 159 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
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