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Synthesis of β-phenylethylamine derivatives VII: The enantiomers of erythro-1-(4′-hydroxyphenyl)-2-(1″-methyl-2″-phenoxyethylamino)-propanol-1

✍ Scribed by J. van Dijk; H. D. Moed

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
698 KB
Volume
80
Category
Article
ISSN
0165-0513

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✦ Synopsis

Abstract

The resolution of racemic erythro‐i‐(4′‐hydroxyphenyl)‐2‐(1″‐methyl‐2″‐phenoxyethylamino)propanol‐1 (Caa 40Name used in the pharmacological tests. Commercial name “Duvadilan”, N.V. Philips‐Duphar.

) is described. The absolute configuration of the three asymmetric centres of the enantiomers is established.

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