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Synthesis of β-Amino Acids via Catalyst- and Solvent-Free Aza-Michael Reaction

✍ Scribed by Bo ZOU; Huan-Feng JIANG

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
100 KB
Volume
26
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

A safe, environmentally friendly and cost‐effective method for the synthesis of β‐amino acid derivatives has been developed. Treatment of α,β‐unsaturated compounds with aliphatic amines furnishes β‐amino acid derivatives in good to excellent yields via a catalyst‐ and solvent‐free aza‐Michael addition.

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