Synthesis of α-trifluoromethyl-α-hydroxycarboxylate dervatives and their phosphorus-containing analogs with the use of fluorinated diazo compounds
✍ Scribed by I. D. Titanyuk; D. V. Vorob’eva; S. N. Osipov; I. P. Beletskaya
- Book ID
- 111465353
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2010
- Tongue
- English
- Weight
- 564 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1070-4280
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📜 SIMILAR VOLUMES
N-t-Butylacetamidines 1 on heating with methyl vinyl ketone, acrolein or crotonaldehyde gave the 2,3-dihydropyridine derivatives 4, 5 or 6 via N-alkylation of the acetamidines 1. Reaction of amidines 1 with phenyl 1-propenyl ketone, benzalacetone or chalcone gave 3,4-dihydropyridine derivatives 8, 9
N-t-Butylacetamidines 1 on heating with methyl acrylate (2) at 200˚ gave the 4,5-dihydro-3H-pyridin-2one derivatives 5. Michael addition of the acetamidines 1 as their ene-1,1-diamine tautomers 1' to 2 and the subsequent cyclization of the adducts gave derivatives 5. Amidines 1 on reaction with trim