Synthesis of α-stannyl α,β-unsaturated carboxylic esters
✍ Scribed by Antonio J. Zapata; Corina Fortoul R.; Carola Acuña A.
- Book ID
- 107812375
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 604 KB
- Volume
- 448
- Category
- Article
- ISSN
- 0022-328X
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📜 SIMILAR VOLUMES
Ethyl a-phenylchalcogeno a,b-unsaturated esters were prepared in a stereoselective manner by the reaction of ethyl propiolates with organocuprates, followed by the reaction with the appropriate electrophilic organosulfur, organoselenium or organotellurium source.
The reactions of (2-trimethylsilanylmethyl) a,b-unsaturated carboxylic ethyl esters with NsONHCO 2 Et and CaO produce, after treatment with AcOH, a-methylene N-(ethoxycarbonyl) b-amino carboxylic esters through ring opening and elimination of the trimethylsilyl group from the intermediate aziridine.