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Synthesis of α-Isocyano-α-alkyl(aryl)acetamides and Their Use in the Multicomponent Synthesis of 5-Aminooxazole, Pyrrolo[3,4-b]pyridin-5-one and 4,5,6,7-Tetrahydrofuro[2,3-c]pyridine.

✍ Scribed by Aude Fayol; Christopher Housseman; Xiaowen Sun; Pierre Janvier; Hugues Bienayme; Jieping Zhu


Publisher
John Wiley and Sons
Year
2005
Weight
25 KB
Volume
36
Category
Article
ISSN
0931-7597

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Preparation of 7-Arylmethyl-1H-pyrrolo[3,4-c]pyridine-1,3-(2H)diones and α-Aryl-3-hydroxy-5-pyridylacetonitriles Using Arynic Methodology. -The use of the reverse addition arynic procedure provides a convenient one-pot, low-temperature route to the title compounds (III) and (V) in modest yields. -