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Synthesis of α- and β-methyl derivatives of 2-[(5-methoxy-1-methyl)indol-2-yl]ethylamine as selective inhibitors of monoamine oxidases A and B.

✍ Scribed by Concepción Fernández García; José L. Marco; E. Fernández Alvarez


Book ID
108372319
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
737 KB
Volume
48
Category
Article
ISSN
0040-4020

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Regiospecific synthesis of 5-(1H-indol-2
✍ Reddeppareddy Dandu; Ming Tao; Kurt A. Josef; Edward R. Bacon; Robert L. Hudkins 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 286 KB

## Abstract magnified image A regiospecific approach to each __N__‐methyl‐5‐(1__H__‐indol‐2‐yl)‐6,7‐dihydro‐2__H__‐indazole isomer is reported. The 1‐methyl isomer **1** was prepared from 5‐bromo‐1‐methyl‐6,7‐dihydro‐1__H__‐indazole **3** and indole‐2‐boronate **5** by palladium catalyzed Suzuki c