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Synthesis of vitamin b6 derivatives. II. 3-Hydroxy-4-hydroxymethyl-2-methyl-5-pyridine acetic acid and related substances

✍ Scribed by Isao Tomita; Houston G. Brooks; David E. Metzler


Book ID
112121436
Publisher
Journal of Heterocyclic Chemistry
Year
1966
Tongue
English
Weight
588 KB
Volume
3
Category
Article
ISSN
0022-152X

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Synthesis of deuterated 2-amino-1-methyl
✍ Mary J. Tanga; James E. Bupp; Wallace W. Bradford πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 95 KB

## Abstract The syntheses of the deuterium‐labeled food mutagen 2‐amino‐1‐methyl‐6‐phenyl‐1H‐imidazo[4,5‐b]pyridine (PhIP) and its __N__‐hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Labeled PhIP–^2^H~5~ is nitrosated t